CTICasesDiffuse Pulmonary Ossification with Mild Fibrosis
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[...]. Diffuse Pulmonary Ossification with Mild Fibrosis. CTICases. Published May 29, 2015. https://str-case-explorer.pages.dev/c/69tbv
Imaging findings
Chest radiograph shows reticulation, particularly in the lower lobes. CT reveals numerous small calcifications or ossifications, predominantly perilymphatic and subpleural, also seen along fissures and interlobular septa. These are associated with mild pulmonary fibrosis, forming pseudo plaques.
Key takeaways
Diffuse pulmonary ossification is typically seen with indolent pulmonary fibrosis, allowing time for ossification to form, distinguishing it from rapidly progressive idiopathic pulmonary fibrosis. It can also occur idiopathically (DPO) or be associated with amyloidosis. The pattern of ossification is perilymphatic and subpleural.
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