CTICasesDiaphragmatic Atrophy and Fatty Replacement in Polymyositis
[...]. Diaphragmatic Atrophy and Fatty Replacement in Polymyositis. CTICases. Published August 12, 2016. https://str-case-explorer.pages.dev/c/828fu
Imaging findings
Serial CT scans demonstrate progressive atrophy and fatty replacement of the diaphragm crura and paraspinal muscles, with the diaphragm crura becoming increasingly ill-defined and almost invisible over time. This correlates with diminished lung volumes.
Key takeaways
Polymyositis can cause severe muscle atrophy and fatty replacement of respiratory muscles, including the diaphragm, leading to respiratory insufficiency. Disuse atrophy from prolonged mechanical ventilation may further exacerbate this process. Serial imaging can demonstrate this progression.
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