CTICasesResolved Transcatheter Aortic Valve Replacement (TAVR) Leaflet Thrombosis
[...]. Resolved Transcatheter Aortic Valve Replacement (TAVR) Leaflet Thrombosis. CTICases. Published February 10, 2017. https://str-case-explorer.pages.dev/c/kwzvg
Imaging findings
Cardiac CT one month after transcatheter aortic valve replacement (TAVR) demonstrates extensive thickening and restricted motion of all three bioprosthetic valve leaflets, consistent with multi-leaflet thrombosis. A follow-up scan after a few months of anticoagulation therapy shows complete resolution of the thrombus with normal leaflet thickness and restoration of normal leaflet motion.
Key takeaways
Subclinical leaflet thrombosis is a recognized complication of bioprosthetic aortic valves, including TAVR, which can lead to elevated transvalvular gradients and early valve degeneration. Multi-detector CT (MDCT) is highly sensitive for identifying hypo-attenuating leaflet thickening (HALT) and hypo-attenuation affected motion (HAM), which typically respond well to oral anticoagulation therapy.
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