CTICasesSecondary Pulmonary Hemosiderosis from Mitral Heart Disease
[...]. Secondary Pulmonary Hemosiderosis from Mitral Heart Disease. CTICases. Published April 23, 2020. https://str-case-explorer.pages.dev/c/uga5m
Imaging findings
CT chest shows chronic pulmonary congestion, diffuse ground-glass opacities, and permanent, thickened interlobular septal lines (Kerley B lines) that do not clear after diuresis. The patient has a history of severe mitral regurgitation/stenosis and underwent transapical TMVR.
Key takeaways
Chronic pulmonary venous hypertension from long-standing mitral valve disease can lead to low-grade alveolar hemorrhage and secondary pulmonary hemosiderosis. The accumulation of hemosiderin-laden macrophages in the interstitium prompts progressive fibrosis, presenting as permanent septal lines and ground-glass opacities that mimic primary interstitial lung disease.
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