CTICasesCardiac Amyloidosis
[...]. Cardiac Amyloidosis. CTICases. Published March 31, 2017. https://str-case-explorer.pages.dev/c/6vb6f
Imaging findings
Cardiac MRI demonstrates severe, concentric left ventricular hypertrophy, mild right ventricular hypertrophy, and bi-atrial enlargement. Late gadolinium enhancement imaging shows a characteristic diffuse, subendocardial enhancement pattern, and the myocardium cannot be nulled during the inversion recovery scout sequence despite standard TI adjustments.
Key takeaways
Cardiac amyloidosis is a classic infiltrative cardiomyopathy characterized by extracellular amyloid deposition. Key cardiac MRI findings include concentric ventricular wall thickening, bi-atrial dilatation, diffuse subendocardial LGE, and a hallmark inability to null the myocardium due to altered gadolinium kinetics. Endomyocardial biopsy remains the gold standard for diagnostic confirmation.
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