CTICasesPaecilomyces variotii Pulmonary Infection
[...]. Paecilomyces variotii Pulmonary Infection. CTICases. Published April 28, 2017. https://str-case-explorer.pages.dev/c/r52hb
Imaging findings
Chest CT shows a large, dense, nodular pulmonary consolidation surrounded by a prominent halo of ground-glass attenuation in the right lower lobe, resembling angioinvasive aspergillosis or mucormycosis. Sputum culture grew Paecilomyces variotii.
Key takeaways
Paecilomyces variotii is an opportunistic, thermophilic soil fungus that can cause invasive pulmonary disease in severely immunocompromised hosts. In patients on active voriconazole prophylaxis for aspergillosis, breakthrough fungal infections are typically caused by resistant species, including zygomycetes (Mucor) or rare opportunistic molds like Paecilomyces.
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