CTICasesLymphocytic Interstitial Pneumonia (LIP), Follicular Bronchiolitis, and MALT Lymphoma in Sjogren's Syndrome
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[...]. Lymphocytic Interstitial Pneumonia (LIP), Follicular Bronchiolitis, and MALT Lymphoma in Sjogren's Syndrome. CTICases. Published September 24, 2015. https://str-case-explorer.pages.dev/c/zkqyw
Imaging findings
The patient exhibited classic findings of cystic lung disease consistent with Lymphocytic Interstitial Pneumonia (LIP). A right middle lobe nodule/mass was identified and removed. Additionally, other nodules were present in the lung parenchyma.
Key takeaways
This case demonstrates the continuum of lymphoid proliferations seen in patients with Sjogren's syndrome, encompassing follicular bronchiolitis, lymphocytic interstitial pneumonia (LIP), and MALT (mucosa-associated lymphoid tissue) lymphoma. Histopathology confirmed both LIP and follicular bronchiolitis, while a resected mass was diagnosed as MALT lymphoma. The presence of other nodules raises the question of whether they represent benign lymphoid tissue or multifocal MALT lymphoma. This spectrum highlights the complex interplay of immune dysregulation in Sjogren's.
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