Warfarin-Induced Tracheobronchial Calcification
[...]. Warfarin-Induced Tracheobronchial Calcification. CTICases. Published May 13, 2021. https://str-case-explorer.pages.dev/c/bjacx
Imaging findings
CT shows diffuse, dense, circumferential calcification of the tracheobronchial tree (bronchial walls) in a relatively young patient, extending down into the lobar and segmental branches.
Key takeaways
Long-term warfarin therapy is a well-known cause of tracheobronchial calcification. Warfarin inhibits vitamin K-dependent gamma-carboxylation of matrix Gla protein (MGP), a potent local inhibitor of tissue calcification, thereby leading to accelerated calcification of cartilaginous structures. It is typically a benign, asymptomatic finding.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Atrial-Esophageal FistulaDevices & Post-op
- Aortic Intramural Hematoma from Intra-Aortic Balloon Pump InjuryAorta & Arteries
- Fabry DiseaseCardiomyopathy
- Bronchogenic CystCongenital
- Cytokine Release Syndrome and Pulmonary Toxicity post CAR-T Cell TherapyIatrogenic
- Bochdalek HerniaCongenital
- Left Ventricular HemangiomaMasses
- Pulmonary Sarcoidosis (Fairy Ring Sign)Autoimmune
See all cases from May 13, 2021 →
Related Iatrogenic cases
- Ruptured Dobhoff Feeding Tube
- CellCept-Induced Pneumatosis Intestinalis
- Pulmonary Lymphedema secondary to Sarcoid-like Lymphadenopathy (Humira-Induced)
- Iatrogenic Pulmonary Infarction after Metastasectomy
- Iatrogenic Left Hemidiaphragm Injury with Gastrothorax
- Alpha-1 Antitrypsin Deficiency treated with Endobronchial Valve Lung Volume Reduction