CTICasesMucinous adenocarcinoma arising in type 1 CPAM
[...]. Mucinous adenocarcinoma arising in type 1 CPAM. CTICases. Published November 8, 2019. https://str-case-explorer.pages.dev/c/fy7p4
Imaging findings
CT scan shows chronic cystic and ground-glass abnormalities in the right middle lobe, which had been treated as recurrent pneumonia, along with multifocal mucinous adenocarcinoma in the right lower lobe and left upper lobe. Biopsy and resection confirmed mucinous adenocarcinoma arising from a type 1 congenital pulmonary airway malformation (CPAM).
Key takeaways
Congenital pulmonary malformations like CPAMs carry a risk of malignant transformation in adults, most commonly into mucinous adenocarcinoma. Recurrent localized infections in a cystic lung lesion should prompt evaluation for an underlying congenital anomaly and associated malignancy.
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